Concurrent administration of cimetidine and tricyclic antidepressants can produce clinically significant increases in pamelor online jotta the plasma concentrations of the tricyclic antidepressant. Patients and their families or other caregivers should discuss all treatment choices with the healthcare provider, not just the use of antidepressants. Dangerous elevations in blood pressure may occur if TCA are combined with clonidine Catapres, Catapres-TTS. If consciousness is impaired, the airway should be secured prior to lavage. Furthermore, whenever one of these other drugs is withdrawn from co-therapy, an increased dose of tricyclic antidepressant may be required. It is strongly recommended that the physician contact the local poison control center for specific pediatric treatment. However, hemodialysis, peritoneal dialysis, exchange transfusions, and forced diuresis generally have been reported as ineffective in tricyclic antidepressant poisoning.